Mapping of functional neural pathways by autoradiographic survey of local metabolic rate with (14C)deoxyglucose.

نویسندگان

  • C Kennedy
  • M H Des Rosiers
  • J W Jehle
  • M Reivich
  • F Sharpe
  • L Sokoloff
چکیده

An enzymatic preparation from human brain converts tryptamine to tryptoline (9H-1,2,3,4-tetrahydropyrido(3,4-b)indole) in the presence of 5-methyltetrahydrofolic acid. Similarly, N-methyltryptamine and 5-hydroxytryptamine yield 1-methyltryptoline and 5-hydroxytryptoline, respectively. Neither in vitro nor in vivo formation of these compounds by human tissues has been described.

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عنوان ژورنال:
  • Science

دوره 187 4179  شماره 

صفحات  -

تاریخ انتشار 1975